The rapid spread of COVID-19 in our country and its consequences have caused some changes in our leisure and work patterns. Dental professionals have not been left behind and several medical organizations have launched protocols and clinical recommendations. Among the latter, the use of cetylpyridinium chloride (CPC) as a prophylactic measure prior to dental procedures to reduce the viral load in the oral cavity, with the aim of preventing the transmission of viral diseases in the dental clinic, stands out.


Do you want to know a little more about how your dental hygiene can be improved with Cetylpyridinium Chloride and what preventive effects it has?


Cetylpyridinium Chloride (CPC) allows the degradation of the lipid bilayer of the envelope of several strains of influenza virus, which suggests its effectiveness against other viruses with similar envelopes, such as respiratory syncytial virus or coronaviruses. CPC has a substantivity of between 3 to 5 hours, is monocationic in nature, soluble in alcohol and in aqueous solutions, can act as a detergent and antiseptic, is not corrosive, neither oxidant and has a neutral pH.


Oral hygiene advice on COVID-19


Although we already talked about it extensively in this post, if you want to avoid oral diseases you must follow some simple hygiene guidelines:

  1. Brush at least three times a day and supplement the brushing with an appropriate mouthwash.
  2. Wash your hands before and after brushing. Don't forget to rinse and dry the brush well.
  3. Do not share your toothbrush and change it every few months, before your bristles get damaged.
  4. If you have any ailment or disorder, go to the dentist. Apart, of course, from the periodic visits for revision.

Mouthwashes play an important role in the daily oral hygiene routine because they have the ability to reach all areas of the oral cavity (gums, palate, less accessible areas) and provide benefits according to their composition: if they contain fluoride They help to remineralise the enamel, if they contain antiseptics they help to control the formation of bacterial plaque, there are also vitamins that help to care for the oral mucous membranes in an integral manner.

The numerous studies carried out on the coronavirus and its ways of spreading seem unanimous in considering the mouth as one of the main access routes of the virus to our organism. The tongue, in particular, is an important site of accumulation of the virus. Given this premise, the need to maintain proper oral hygiene seems obvious.


Let's talk about mouthwashes: Cetylpyridinium chloride or chlorhexidine?


Two types of antiseptics are usually used in dentistry: chlorhexidine, which continues to be the most effective agent in controlling biofilm and treating periodontal diseases of bacterial origin, because of its broad spectrum of action against Gram + and Gram - microorganisms; and cetylpyridinium chloride (CPC), a broad-spectrum antiseptic against bacteria, viruses and fungi.

There are also mouthwashes that include both antiseptics in their formulation for total coverage, such as our KIN Gingival Complex as it incorporates chlorhexidine at 0.12%, cetylpyridinium chloride at 0.05% and Alpantha which gives it toning and strengthening properties on mucous membranes and gums.

Gargle or rinse with mouthwashes containing cetylpyridinium chloride and therefore lower your mouth's viral load. However, keep in mind that those recommended for home and clinical use are those with a 0.05% concentration of cetylpyridinium chloride. Therefore, when choosing the mouthwash with which you are going to take care of your oral health, make sure that its composition includes this percentage of CPC.

As a significant document on the use of mouthwashes and their hygienic basis against coronavirus, the "Strategic action plan for the period of de-escalation COVID-19", published by the Spanish Council of Dentists, indicates a series of prophylactic measures for the dental clinic that includes in its third section, the rinsing with CPC before, during and after the treatments to the patients.


Kin products with cetylpyridinium chloride:



KIN Gingival Complex

Its formula includes chlorhexidine 0.12%, Alpantha and cetylpyridinium chloride 0.05%. Indicated for intensive care of the gums, its use is recommended for periods between 2 and 3 weeks, or as directed by your dentist.

KIN Gingival Complex Toothpaste

GingiKIN B5

Contains 0.05% cetylpyridinium chloride, zinc citrate, provitamin B5, vitamin B3, fluoride and xylitol. Ideal for daily care of the gums.

Mouthwash with cetylpyridinium chloride gingikin b5


With aloe vera, fluoride, provitamin B5 and cetylpyridinium chloride 0.05%. It is an ideal line designed for daily care in the family environment.


You can choose the line that best suits your needs and that you like the most. These products are available in pharmacies and parapharmacies.


Do you know our pharmacy search engine? Find the KIN products at your nearest pharmacy: KIN pharmacy search.

And now that we have seen the properties of antiseptics in mouthwashes, are you clear that a good mouthwash is your best ally to complement your daily oral hygiene?



  1. Mouthwashes and their effect against Covid-19 -
  2. CPC mouthwashes: the most effective mouthwashes against coronavirus -
  3. Colegio de Higienistas de Madrid - COVID-19: ORAL HYGIENE RECOMMENDATIONS. –
  4. Dentists' Council - Strategic action plan for dental clinics during the de-escalation period -